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Como os adesivos cutâneos de CBD de 15 mg se comparam aos produtos orais de CBD em termos de duração do alívio da dor?

Como os adesivos cutâneos de CBD de 15 mg se comparam aos produtos orais de CBD em termos de duração do alívio da dor? Os adesivos proporcionam uma liberação constante durante 8–24 horas, enquanto o CBD oral tem uma duração mais curta devido ao colapso digestivo. O CBD oral sofre metabolismo de primeira passagem, reduzindo a sua biodisponibilidade e necessitando de doses mais elevadas. Os adesivos transdérmicos contornam esse processo, garantindo efeitos terapêuticos prolongados com menos flutuações. Estudos confirmam que o CBD transdérmico oferece um alívio da dor mais consistente e prolongado do que as formulações orais (Paudel et al., 2010).

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