How do cannabinoids like CBD and THC affect Endocannabinoid System balance?
How do cannabinoids like CBD and THC affect Endocannabinoid System balance? Cannabinoids like CBD and THC affect the balance of the Endocannabinoid System by interacting with cannabinoid receptors and influencing endocannabinoid production. THC binds to CB1 receptors in the brain, activating them and producing psychoactive effects, while CBD has a more modulating role, interacting with both CB1 and CB2 receptors without producing a high. CBD also enhances the body’s natural levels of endocannabinoids by inhibiting enzymes that break them down, such as FAAH. These effects help the ECS maintain homeostasis, regulating functions like pain, mood, appetite, and immune response. The balance of these cannabinoids influences the overall health and functioning of the ECS.