How does CBD influence the Endocannabinoid System in reducing pain sensitivity?
How does CBD influence the Endocannabinoid System in reducing pain sensitivity? CBD influences the Endocannabinoid System in reducing pain sensitivity by interacting with CB1 and CB2 receptors, which are involved in pain processing and inflammation. CBD helps to increase endocannabinoid levels, particularly anandamide, which reduces pain perception by inhibiting pain signal transmission in the nervous system. Additionally, CBD modulates neurotransmitter release, such as glutamate and substance P, which are involved in pain sensation. It also has anti-inflammatory effects, which further reduce pain associated with conditions like arthritis or nerve injury. Through these mechanisms, CBD helps to lower pain sensitivity and improve pain management.