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Kako CBN djeluje s kanabinoidnim receptorima i kako to utječe na njegova psihoaktivna svojstva?

Kako CBN djeluje s kanabinoidnim receptorima i kako to utječe na njegova psihoaktivna svojstva? CBN prvenstveno djeluje s CB1 i CB2 receptorima u endokanabinoidnom sustavu, iako je njegov afinitet za CB1 relativno nizak u usporedbi s THC-om. Blaga interakcija CBN-a s CB1 receptorima rezultira manje izraženim psihoaktivnim učincima, što dovodi do manje intenzivnog "high". Umjesto toga, CBN ispoljava svoje umirujuće i sedativne učinke potičući opuštanje i smanjujući hiperaktivnost u živčanom sustavu. Također ima jači afinitet za CB2 receptore, gdje može ispoljavati protuupalne učinke, dodatno smanjujući stres i potičući opuštanje. Ova interakcija receptora čini CBN korisnim u terapeutske svrhe gdje je poželjan blaži učinak.

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