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Kako THC i CBD međusobno djeluju kako bi utjecali na funkciju mitohondrija u neuronima?

Kako THC i CBD međusobno djeluju kako bi utjecali na funkciju mitohondrija u neuronima? THC i CBD djeluju na funkciju mitohondrija u neuronima utječući na stanične signalne putove koji reguliraju proizvodnju energije, oksidativni stres i neuroprotekciju. THC-ova aktivacija CB1 receptora može promijeniti potencijal mitohondrijske membrane i povećati proizvodnju reaktivnih kisikovih vrsta (ROS), potencijalno pridonoseći oksidativnom stresu. Nasuprot tome, pokazalo se da CBD ima antioksidativna svojstva koja štite mitohondrije od oksidativnog oštećenja, poboljšavaju zdravlje mitohondrija i promiču neuroprotekciju. Zajedno, THC i CBD mogu imati komplementarne učinke na funkciju mitohondrija, pri čemu THC potencijalno izaziva oksidativni stres, a CBD se suprotstavlja tom oštećenju smanjenjem upale i oksidativnog oštećenja neurona.

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