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Koje su razlike u učincima THC-a na CB1 receptore koji se nalaze u različitim regijama mozga?

Koje su razlike u učincima THC-a na CB1 receptore koji se nalaze u različitim regijama mozga? Učinci THC-a na CB1 receptore variraju ovisno o uključenoj regiji mozga, s različitim učincima na regije poput hipokampusa, prefrontalnog korteksa i strijatuma. U hipokampusu, THC ometa kodiranje i vraćanje memorije, dok u prefrontalnom korteksu oštećuje izvršne funkcije kao što su donošenje odluka i pažnja. Strijatum, uključen u sustav nagrađivanja, pokazuje povećano otpuštanje dopamina kao odgovor na THC, pridonoseći njegovim okrepljujućim i euforičnim učincima. Interakcija THC-a s CB1 receptorima u tim regijama dovodi do različitih kognitivnih i emocionalnih ishoda, utječući na zadatke poput formiranja pamćenja i kontrole impulsa. Različiti utjecaji na CB1 receptore u regijama mozga naglašavaju složenost psihoaktivnih učinaka THC-a.

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