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How do CBD and THC modulate the production of pain-related neurotransmitters in neuropathic pain patients?

How do CBD and THC modulate the production of pain-related neurotransmitters in neuropathic pain patients? CBD and THC regulate pain by modulating neurotransmitters like glutamate and GABA through the endocannabinoid system. THC activates CB1 receptors, reducing pain perception by inhibiting excitatory neurotransmitter release. CBD enhances this effect by interacting with TRPV1 receptors and reducing inflammation, which indirectly lowers pain signaling. This combination is highly effective in managing neuropathic pain by addressing both central and peripheral mechanisms. It provides sustained relief without the side effects of traditional pain medications.
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