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How do different patch designs influence cannabinoid permeation and overall therapeutic efficacy?

How do different patch designs influence cannabinoid permeation and overall therapeutic efficacy? Patch designs that utilize different materials, such as hydrophilic or lipophilic matrices, can influence cannabinoid permeation by affecting the rate of diffusion through the skin. The adhesive type and layer thickness can impact how well the cannabinoids stay in contact with the skin, which directly affects absorption. Microencapsulation and controlled-release technologies can regulate the release of cannabinoids, ensuring consistent therapeutic effects over time. Proper design ensures that cannabinoids penetrate deeper into the dermal layers for maximum efficacy.

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