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How do variations in skin thickness and skin type affect the penetration depth of cannabinoids from CBD patches?

How do variations in skin thickness and skin type affect the penetration depth of cannabinoids from CBD patches? Thicker skin, such as on the palms or soles, may present a barrier to cannabinoid penetration, reducing the depth to which cannabinoids can travel and impacting the overall effectiveness of the patch. Conversely, areas with thinner skin, like the inner arm or behind the ear, allow for more efficient absorption and deeper penetration. Skin type, including whether it is oily or dry, also plays a role in absorption, as dry skin may be less permeable. Tailoring the patch to specific areas with thinner or more permeable skin may enhance cannabinoid delivery.

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