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What are the current challenges in establishing evidence-based guidelines for cannabinoid use in clinical practice?

What are the current challenges in establishing evidence-based guidelines for cannabinoid use in clinical practice? Current challenges in establishing evidence-based guidelines for cannabinoid use in clinical practice include limited research, regulatory hurdles, and varying state laws regarding cannabis. The need for more large-scale, randomized controlled trials restricts the ability to draw definitive conclusions about cannabinoid efficacy and safety. Additionally, the diverse nature of cannabinoid products complicates standardization and dosage recommendations, making it difficult for clinicians to provide consistent care. Addressing these challenges requires increased funding for research, collaboration between stakeholders, and the development of clear regulatory frameworks to guide clinical practice in cannabinoid use (Parker et al., 2021).
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