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Hoe verandert de aanwezigheid van THC in cannabistincturen de farmacokinetiek en therapeutische effecten van CBD voor chronische pijnverlichting? De aanwezigheid van THC in cannabistincturen verandert de farmacokinetiek en therapeutische effecten van CBD voor chronische pijnverlichting door de biologische beschikbaarheid en synergetische effecten van beide cannabinoïden te verbeteren. THC helpt de opname en effectiviteit van CBD te verbeteren door de bloedstroom en de permeabiliteit door de celmembranen te vergroten. CBD kan op zijn beurt de psychoactieve effecten van THC moduleren, waardoor potentiële angst wordt verminderd en de pijnverlichting wordt verbeterd zonder significante cognitieve stoornissen te veroorzaken. Samen werken THC en CBD synergetisch om pijn en ontstekingen te verminderen, waarbij THC voor een directere verlichting zorgt en CBD de duur van de effecten verlengt. Deze combinatie verbetert het algehele therapeutische resultaat voor patiënten met chronische pijn.
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