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Hvordan ændrer CBD THC-inducerede ændringer i inflammatoriske signalveje?

Hvordan ændrer CBD THC-inducerede ændringer i inflammatoriske signalveje? CBD kan ændre THC-inducerede ændringer i inflammatoriske signalveje ved at udøve antiinflammatoriske virkninger gennem dets interaktion med CB2-receptorer og andre ikke-cannabinoide veje. THC, når det bruges alene, kan fremme inflammatoriske reaktioner, især når CB1-receptorer aktiveres i mikrogliaceller, hvilket kan forværre neuroinflammation. CBD kan på den anden side reducere inflammation ved at hæmme produktionen af ​​pro-inflammatoriske cytokiner og modulere NF-KB-signalvejen. Denne dobbelte interaktion kan give en terapeutisk balance, hvor CBD mindsker THC's potentiale til at udløse skadelige inflammatoriske reaktioner. Den kombinerede brug af THC og CBD kan derfor tilbyde en mere sikker profil for patienter med tilstande, der involverer inflammation, såsom neurodegenerative sygdomme.

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