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Hvordan påvirker THC og CBD inflammatorisk cytokinfrigivelse forskelligt?

Hvordan påvirker THC og CBD inflammatorisk cytokinfrigivelse forskelligt? THC og CBD påvirker inflammatorisk cytokinfrigivelse gennem forskellige mekanismer. THC aktiverer CB1- og CB2-receptorer, som kan inducere immunundertrykkelse og pro-inflammatorisk cytokinproduktion ved høje doser, hvilket bidrager til immundysregulering i visse sammenhænge. CBD modulerer imidlertid CB2-receptorer og har antiinflammatoriske virkninger, hvilket reducerer frigivelsen af ​​pro-inflammatoriske cytokiner som TNF-α og IL-6. Derudover påvirker CBD også andre veje, såsom TRPV1-receptorer, for at forbedre dets antiinflammatoriske egenskaber. Mens THC kan fremkalde betændelse i visse sammenhænge, ​​har CBD en tendens til at reducere denne reaktion, hvilket gør kombinationen nyttig til tilstande, der involverer kronisk inflammation.

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