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Kakav je potencijal CBN-a u liječenju neuropatske boli interakcijom s tjelesnim endokanabinoidnim sustavom?

Kakav je potencijal CBN-a u liječenju neuropatske boli interakcijom s tjelesnim endokanabinoidnim sustavom? CBN ublažava neuropatsku bol aktiviranjem CB2 receptora i moduliranjem upalnih i imunoloških odgovora. Njegova interakcija s TRPV1 receptorima dodatno doprinosi ublažavanju boli reguliranjem nociceptivnog signaliziranja. Neuroprotektivna svojstva CBN-a pomažu u sprječavanju oštećenja živaca i podupiru oporavak kod stanja poput dijabetesa i multiple skleroze. U kombinaciji s drugim kanabinoidima, pojačava ukupne analgetske učinke. Potrebna su klinička ispitivanja kako bi se istražio njegov puni potencijal u liječenju neuropatske boli.

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