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Kakav je utjecaj CBD-a na promjene izazvane THC-om u procesuiranju nagrada?

Kakav je utjecaj CBD-a na promjene izazvane THC-om u procesuiranju nagrada? Pokazalo se da CBD modulira procesiranje nagrada i smanjuje utjecaj THC-a na dopaminergičku aktivnost. THC povećava otpuštanje dopamina u regijama mozga uključenim u nagrađivanje, kao što je nucleus accumbens, što dovodi do osjećaja euforije i jača put nagrađivanja. Međutim, CBD može oslabiti učinke THC-a na povećanje nagrađivanja utječući na serotonergičke i dopaminergičke sustave, moguće smanjujući vjerojatnost ovisnosti o kanabisu. Dodatno, CBD može vratiti ravnotežu dopaminskog sustava, sprječavajući prekomjernu aktivaciju koja može doprinijeti neprilagodljivom ponašanju nagrađivanja. Ova interakcija sugerira da bi CBD mogao biti koristan u balansiranju pojačavajućih učinaka THC-a, osobito u borbi protiv ovisnosti.

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