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¿Cómo regula el sistema endocannabinoide la función del sistema inmunológico?

¿Cómo regula el sistema endocannabinoide la función del sistema inmunológico? El sistema endocannabinoide regula la función del sistema inmunológico principalmente a través de los receptores CB2, que abundan en las células inmunitarias. Cuando se activan, los receptores CB2 modulan las respuestas inmunitarias, incluida la inflamación y la activación de las células inmunitarias. Los endocannabinoides como el 2-AG y la anandamida se unen a estos receptores para reducir la inflamación excesiva y mantener el equilibrio del sistema inmunológico. Esta regulación ayuda a prevenir la inflamación crónica, los trastornos autoinmunes y el daño tisular. Al ajustar las respuestas inmunes, el sistema endocannabinoide garantiza una defensa adecuada contra los patógenos sin causar daños excesivos a los tejidos sanos.
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