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What role does the gut microbiome play in modulating the effects of cannabinoids on the body?

What role does the gut microbiome play in modulating the effects of cannabinoids on the body? The gut microbiome plays a critical role in modulating the effects of cannabinoids on the body, influencing metabolism, immune function, and overall health. Research suggests that the composition of the gut microbiome can affect the absorption and efficacy of cannabinoids, potentially altering individual responses to cannabinoid therapies. Additionally, the gut microbiome may interact with the endocannabinoid system, impacting inflammation and other physiological processes. This interaction highlights the importance of considering gut health when developing cannabinoid-based treatments and emphasizes the need for further research to understand these complex relationships. Exploring the connection between the gut microbiome and cannabinoids may lead to personalized approaches in cannabinoid therapies (Davis et al., 2020).
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