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In che modo la formulazione dei cannabinoidi differisce per l'uso diurno rispetto a quella notturna nei cerotti transdermici?

In che modo la formulazione dei cannabinoidi differisce per l'uso diurno rispetto a quella notturna nei cerotti transdermici? Le formulazioni per il giorno possono enfatizzare i cannabinoidi non sonnolenti come CBD e CBG per la vigilanza e il sollievo dal dolore. I cerotti notturni spesso contengono cannabinoidi sedativi come CBN o THC per il supporto del sonno. I meccanismi di rilascio controllato regolano i tassi di assorbimento in base ai ritmi circadiani. Formulazioni personalizzate migliorano l’efficienza terapeutica in base alle esigenze del momento della giornata (Russo, 2011).

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