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What are the key challenges in formulating cannabinoid patches with consistent dosing over extended wear periods?

What are the key challenges in formulating cannabinoid patches with consistent dosing over extended wear periods? One challenge in formulating cannabinoid patches with consistent dosing is maintaining the stability and potency of cannabinoids throughout the patch’s wear time. Environmental factors like heat, humidity, and exposure to air can degrade cannabinoids, affecting their efficacy. Additionally, ensuring that the patch adheres well to the skin for extended periods without irritating the skin or losing adhesion is another key challenge. To address these, manufacturers must use protective packaging, stable delivery systems, and high-quality adhesives that ensure consistent performance without compromising safety.

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