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Hva er forskjellene i cannabinoidreseptoraffinitet mellom CBG og CBD?

Hva er forskjellene i cannabinoidreseptoraffinitet mellom CBG og CBD? CBG har en høyere affinitet for både CB1- og CB2-reseptorer sammenlignet med CBD, som har en svakere interaksjon med disse reseptorene. CBG binder seg mer effektivt til CB2-reseptorer, som er involvert i immunsystemmodulering, mens CBD virker mer indirekte på det endocannabinoide systemet. Disse forskjellene i reseptoraffinitet resulterer i distinkte fysiologiske effekter, med CBG som potensielt er mer effektivt for visse terapeutiske bruksområder som smerte- og betennelsesbehandling. I motsetning til dette er CBDs effekter mer utbredt og involverer modulering av andre signalveier (Choi et al., 2021).

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