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Quali sono le considerazioni chiave sulla progettazione dei cerotti con cannabinoidi per garantire un rilascio uniforme e costante nel tempo?

Quali sono le considerazioni chiave sulla progettazione dei cerotti con cannabinoidi per garantire un rilascio uniforme e costante nel tempo? Le considerazioni chiave per la progettazione dei cerotti con cannabinoidi includono la selezione di matrici di rilascio appropriate, come sistemi idrofili o lipofili, che controllano la velocità di diffusione dei cannabinoidi. La formulazione dovrebbe includere cannabinoidi adeguatamente incapsulati o combinati con eccipienti che supportino un rilascio costante, evitando rapidi picchi iniziali. Lo strato adesivo deve garantire il pieno contatto con la pelle per mantenere un'erogazione efficace per tutta la durata dell'uso del cerotto. Inoltre, fattori come la dimensione del cerotto, la permeabilità della pelle e gli oli vettore scelti dovrebbero essere ottimizzati per un rilascio uniforme e costante di cannabinoidi.

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