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CBD yetişkin beynindeki sinaptik plastisiteyi nasıl etkiler?

CBD yetişkin beynindeki sinaptik plastisiteyi nasıl etkiler? CBD, özellikle hipokampus gibi alanlarda endokannabinoid sinyalini modüle ederek ve nörojenezi teşvik ederek yetişkin beynindeki sinaptik plastisiteyi etkiler. CB1 reseptörleri ile etkileşime girerek hafıza ve öğrenme için önemli bir süreç olan uzun vadeli güçlenmeyi (LTP) arttırdığı gösterilmiştir. CBD ayrıca sinaptik aktivite için çok önemli olan glutamat ve GABA sistemlerini modüle ederek nörotransmitter salınımını da etkiler. Bu etkiler bilişsel işlevin ve nöroplastisitenin iyileşmesine katkıda bulunur (Aso ve Ferrer, 2014).

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