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¿Cómo afectan el CBD y el THC a la farmacocinética del cannabis cuando se combinan en productos como aceites, tinturas y comestibles?

¿Cómo afectan el CBD y el THC a la farmacocinética del cannabis cuando se combinan en productos como aceites, tinturas y comestibles? El CBD ralentiza el metabolismo del THC al inhibir las enzimas CYP450, lo que provoca una actividad prolongada del THC y efectos terapéuticos mejorados. Esta interacción también puede reducir el pico de psicoactividad al alterar la absorción y distribución del THC. Juntos, mejoran la biodisponibilidad y proporcionan una liberación más sostenida de cannabinoides. Productos como aceites y tinturas optimizan esta interacción al ofrecer dosis controladas y efectos consistentes. Su farmacocinética combinada garantiza mejores resultados terapéuticos para diversas afecciones.
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