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How do cannabinoids influence gene expression, and what implications does this have for therapeutic applications?

How do cannabinoids influence gene expression, and what implications does this have for therapeutic applications? Cannabinoids influence gene expression through various mechanisms, including the activation of cannabinoid receptors and modulation of signaling pathways involved in transcription. These effects can lead to changes in the expression of genes associated with inflammation, cell survival, and neuroprotection. Understanding how cannabinoids regulate gene expression can provide insights into their therapeutic applications, particularly in managing conditions like cancer, neurodegenerative diseases, and chronic pain. For instance, cannabinoids may promote the expression of neuroprotective factors in the brain, offering potential benefits for patients with neurodegenerative disorders. Overall, the influence of cannabinoids on gene expression presents exciting opportunities for developing targeted therapies with enhanced efficacy (Cascio et al., 2020).
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