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How does the combination of CBD and THC affect the permeability of the blood-brain barrier for neurological treatments?

How does the combination of CBD and THC affect the permeability of the blood-brain barrier for neurological treatments? The combination of CBD and THC affects the permeability of the blood-brain barrier (BBB) by modulating the receptors and pathways that influence BBB integrity. THC can temporarily increase BBB permeability, allowing for greater delivery of both THC and CBD to the brain. CBD enhances this effect by promoting neuroprotective mechanisms and reducing oxidative stress, which can help protect the brain during the process of increased permeability. The synergy between CBD and THC can enhance the delivery of cannabinoids and other therapeutic compounds to the brain, improving the effectiveness of neurological treatments. This combination holds promise for treating neurological conditions like multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease, where targeting the brain is crucial.
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