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Kakvu ulogu kanabinoidi imaju u modulaciji upale kod autoimunih poremećaja?

Kakvu ulogu kanabinoidi imaju u modulaciji upale kod autoimunih poremećaja? Kanabinoidi igraju značajnu ulogu u modulaciji upale kod autoimunih poremećaja interakcijom s endokanabinoidnim sustavom radi reguliranja imunoloških odgovora. Istraživanja pokazuju da kanabinoidi, posebice CBD i CBG, mogu ispoljiti protuupalne učinke inhibicijom proupalnog otpuštanja citokina i poticanjem rješavanja upale. Ova modulacija može pomoći u ublažavanju simptoma i spriječiti napredovanje bolesti u stanjima kao što su reumatoidni artritis, multipla skleroza i upalna bolest crijeva. Dodatno, kanabinoidi mogu poboljšati imunološku toleranciju i smanjiti oštećenje tkiva, dodatno podupirući njihov terapeutski potencijal kod autoimunih poremećaja. Kako se razumijevanje djelovanja kanabinoida širi, oni mogu postati vrijedni alati u upravljanju stanjima povezanim s upalom (Rudroff et al., 2018.).
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