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Care este rolul canabinoizilor în modularea neuroinflamației în condițiile durerii cronice? Canabinoizii joacă un rol crucial în modularea neuroinflamației în condițiile durerii cronice prin interacțiunea cu receptorii canabinoizi din sistemul nervos central. Activarea acestor receptori poate duce la inhibarea citokinelor proinflamatorii și la o reducere a activării celulelor gliale, ambele fiind implicate în patofiziologia durerii cronice. Cercetările au arătat că canabinoizii pot reduce în mod eficient neuroinflamația, care este adesea asociată cu afecțiuni precum fibromialgia, durerea neuropatică și artrita. Prin atenuarea neuroinflamației, canabinoizii pot ajuta la atenuarea durerii și la îmbunătățirea funcției generale la persoanele afectate (Malfait et al., 2019).
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