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How does the combination of CBD and THC interact with the immune system to reduce systemic inflammation and improve autoimmune conditions?

How does the combination of CBD and THC interact with the immune system to reduce systemic inflammation and improve autoimmune conditions? CBD and THC interact with the immune system by modulating CB2 receptor activity and reducing the release of pro-inflammatory cytokines. THC suppresses overactive immune responses by directly binding to CB2 receptors on immune cells, while CBD indirectly influences these pathways through TRPV1 and adenosine receptors. CBD also enhances the production of regulatory T-cells, which help control autoimmune reactions. Together, they reduce systemic inflammation and improve symptoms in conditions like rheumatoid arthritis and lupus. This combination provides a balanced immunomodulatory effect, reducing both inflammation and immune system overactivation.
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