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How does the type of cannabinoid in the patch (e.g., CBD versus CBG or CBN) influence the diffusion rate through the skin and its overall therapeutic effect?

How does the type of cannabinoid in the patch (e.g., CBD versus CBG or CBN) influence the diffusion rate through the skin and its overall therapeutic effect? The type of cannabinoid in the patch influences both the diffusion rate and the therapeutic effect based on its chemical properties. Cannabinoids like CBD, which are highly lipophilic, generally diffuse more easily through the skin compared to more polar cannabinoids like CBG or CBN. The diffusion rate of each cannabinoid is also affected by its molecular size and interactions with the skin’s lipids. As a result, patch formulations can be tailored to deliver cannabinoids at specific rates, providing either quick relief or sustained effects depending on the therapeutic need.

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