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Hvordan påvirker CBD og THC aktiviteten af mikrogliaceller under neurodegenerative tilstande, især ved Alzheimers og Parkinsons sygdom?

Hvordan påvirker CBD og THC aktiviteten af ​​mikrogliaceller under neurodegenerative tilstande, især ved Alzheimers og Parkinsons sygdom? CBD og THC reducerer neuroinflammation ved at modulere aktiviteten af ​​mikrogliaceller, hjernens immunceller. CBD undertrykker pro-inflammatorisk cytokinfrigivelse og fremmer et skift mod en anti-inflammatorisk mikroglial tilstand, mens THCs interaktion med CB2-receptorer dæmper mikroglial aktivering yderligere. Denne dobbelte handling beskytter neuroner mod oxidativ skade og inflammatorisk stress, og bremser udviklingen af ​​neurodegenerative tilstande som Alzheimers og Parkinsons. Sammen fremmer de et neurobeskyttende miljø ved at reducere kronisk mikroglial overaktivering. Denne synergi understøtter forbedrede resultater i disse sygdomme.
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