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Hvordan påvirker hudhydrering permeabiliteten af cannabinoider i depotplastre, og hvordan kan dette kontrolleres?

Hvordan påvirker hudhydrering permeabiliteten af ​​cannabinoider i depotplastre, og hvordan kan dette kontrolleres? Hudhydrering spiller en væsentlig rolle i cannabinoidpermeabilitet ved at påvirke hudens barrierefunktion. Velhydreret hud har en tyndere, mere fleksibel barriere, som letter optagelsen af ​​cannabinoider. Dehydreret hud kan på den anden side hæmme cannabinoid penetration. For at kontrollere hydrering kan formuleringer omfatte fugtighedsbevarende midler såsom glycerin eller hyaluronsyre, og brugere kan opfordres til at hydrere deres hud før påføring af plaster for at forbedre effektiviteten af ​​cannabinoidtilførsel.

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