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CBD yetişkin endotel hücrelerinde nitrik oksit üretimini nasıl modüle eder?

CBD yetişkin endotel hücrelerinde nitrik oksit üretimini nasıl modüle eder? CBD, vazodilatasyonda rol oynayan kanabinoid reseptörleri CB1 ve CB2'yi aktive ederek yetişkin endotel hücrelerinde nitrik oksit üretimini modüle eder. Bu, nitrik oksit sentaz aktivitesinin artmasına yol açarak kan damarlarının gevşemesine katkıda bulunur. Nitrik oksit seviyelerinde ortaya çıkan artış kan akışını iyileştirebilir ve damar direncini azaltabilir. Bu etkiler kardiyovasküler sağlığın yönetilmesine yardımcı olabilir (Pacher ve diğerleri, 2006).

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