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How can cannabinoid patch design be adjusted for different parts of the body with varying skin permeability, such as the wrists or ankles?

How can cannabinoid patch design be adjusted for different parts of the body with varying skin permeability, such as the wrists or ankles? To optimize cannabinoid absorption, patch design can be adjusted based on skin permeability, which varies across different body areas. Areas like the wrists, with thinner skin and higher blood flow, may benefit from smaller, more concentrated patches, while areas with thicker skin, like the ankles, may require larger or more potent patches for effective absorption. Customizing the adhesive and formulation to account for skin characteristics in each area ensures consistent cannabinoid delivery. This tailored approach maximizes therapeutic effects by considering anatomical differences in skin properties.

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