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How can the chemical structure of minor cannabinoids, such as CBG and CBN, influence their solubility and stability in transdermal CBD patches?

How can the chemical structure of minor cannabinoids, such as CBG and CBN, influence their solubility and stability in transdermal CBD patches? The chemical structure of minor cannabinoids like CBG and CBN affects their solubility in different solvents and formulations. CBG, for example, may have lower solubility in certain skin lipids, requiring the use of specialized carriers or solvents. Additionally, the stability of these cannabinoids in patch formulations can be impacted by factors like exposure to light, heat, or oxygen, requiring the use of stabilizing agents. Understanding these properties ensures that CBG and CBN remain effective and stable in transdermal delivery systems.

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