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Kā mutes gļotādas caurlaidība ietekmē CBD uzsūkšanos no sloksnēm?

Kā mutes gļotādas caurlaidība ietekmē CBD uzsūkšanos no sloksnēm? Mutes gļotādas caurlaidībai ir izšķiroša nozīme CBD uzsūkšanā no sublingvālajām sloksnēm, jo ​​tā nosaka, cik ātri CBD nonāk asinsritē. Gļotādas membrānas ir ļoti vaskularizētas, ļaujot CBD nonākt tieši asinsritē, apejot pirmā loka metabolismu aknās. Uzsūkšanās ātrumu ietekmē tādi faktori kā perorālās sloksnes sastāvs un gļotādas apvalka stāvoklis. Caurlaidīgāka gļotāda veicina ātrāku un efektīvāku CBD uzsūkšanos (Morrison et al., 2015).

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