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Kā CBD metabolisms ietekmē tā pussabrukšanas periodu organismā un kādi faktori ietekmē tā darbības ilguma izmaiņas?

Kā CBD metabolisms ietekmē tā pussabrukšanas periodu organismā un kādi faktori ietekmē tā darbības ilguma izmaiņas? CBD metabolismu ietekmē tādi faktori kā aknu enzīmu aktivitāte, ievadīšanas metode un individuāli faktori, piemēram, ģenētika un ķermeņa uzbūve. CBD galvenokārt metabolizē citohroma P450 enzīmu sistēma, kas dažādiem indivīdiem var atšķirties, ietekmējot tā pussabrukšanas periodu. Lietojot iekšķīgi, CBD tiek pakļauts pirmā loka metabolismam aknās, kas var samazināt tā biopieejamību un pagarināt tā pusperiodu. CBD darbības ilgumu var ietekmēt arī citi faktori, piemēram, vecums, aknu darbība un blakusslimību klātbūtne. Rezultātā CBD pussabrukšanas periods var atšķirties, un atkarībā no šiem faktoriem iedarbība ilgst no 2 līdz 8 stundām.

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