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¿Cuáles son las propiedades farmacológicas únicas del CBN en comparación con otros cannabinoides como el THC y el CBD? El CBN, o cannabinol, es un cannabinoide con propiedades farmacológicas únicas, derivadas principalmente de sus leves efectos psicoactivos y sus potenciales propiedades sedantes. A diferencia del THC, que es un potente agonista de los receptores CB1, el CBN tiene menor afinidad por estos receptores y puede exhibir efectos sedantes sin causar una psicoactividad significativa. Además, se cree que el CBN potencia los efectos de otros cannabinoides, en particular para promover el sueño. Por el contrario, el CBD no es psicoactivo y funciona principalmente como antagonista de los receptores CB1. Las propiedades distintivas del CBN sugieren su potencial para aplicaciones en trastornos del sueño y como componente sinérgico en formulaciones de cannabinoides (Stark et al., 2020).
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