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Hoe presteren cannabinoïdepleisters bij ouderen, vooral wat betreft absorptie en bijwerkingen?

Hoe presteren cannabinoïdepleisters bij ouderen, vooral wat betreft absorptie en bijwerkingen? Bij een ouder wordende huid is het lipidengehalte verlaagd, wat de transdermale absorptiesnelheid kan veranderen. Een langzamer metabolisme bij oudere personen kan leiden tot een verlengde circulatie van cannabinoïden, waardoor dosisaanpassingen nodig zijn. Door de kwetsbaarheid van de huid zijn zachte lijmen nodig om irritatie te voorkomen. Er zijn klinische onderzoeken nodig om de werkzaamheid en veiligheid van de pleisters voor oudere gebruikers te optimaliseren (Baswan et al., 2020).

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