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Kakvi su učinci THC-a i CBD-a na neuropeptidnu signalizaciju u mozgu?

Kakvi su učinci THC-a i CBD-a na neuropeptidnu signalizaciju u mozgu? THC i CBD utječu na signalizaciju neuropeptida u mozgu, iako na različite načine. THC aktivira CB1 receptore, što dovodi do modulacije neuropeptida uključenih u regulaciju boli, stresa i raspoloženja, kao što su supstanca P i faktor oslobađanja kortikotropina (CRF). CBD, s druge strane, ne aktivira izravno CB1 receptore, ali stupa u interakciju s drugim receptorima (poput 5-HT1A i TRPV1) kako bi modulirao signalizaciju neuropeptida, često smanjujući upalu i reakcije na stres. Zajedno, THC i CBD mogu pojačati ili inhibirati učinke neuropeptida, ovisno o kontekstu, potencijalno nudeći terapeutske prednosti kod poremećaja raspoloženja i kronične boli. Njihovi kombinirani učinci mogu modulirati oslobađanje neuropeptida, utječući na ponašanje, stres i percepciju boli.

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IMPORTANT: This information is NOT MEDICAL ADVICE and is only provided for general informational purposes only. Always first seek the advice of your doctor or a healthcare professional first before taking a CBD product or vitamin supplement if you are unsure. Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition. No claims are intended to be made about the functions or ability of a CBD infused cosmetic product and/ or vitamin supplement to provide any specific health or wellness benefits. None of our CBD strips, patches or other CBD products are described, promoted or marketed as having any function not listed in the COSING Information Database. Any information provided here about CBD or any other ingredient and/ or product is strictly for general informational purposes and should not be interpreted as medical, therapeutic, or diagnostic advice. CBD products are not intended to diagnose, treat, cure, or prevent any disease or health condition. You are advised to always first consult with a doctor or a qualified healthcare professional before using any CBD product, particularly if you any of the following apply. DO NOT USE CBD IF PREGANT, BREAST FEEDING OR IF YOU HAVE A SERIOUS MEDICAL CONDITION. DO NOT USE IF PACKAGING HAS BEEN OPENED DURING SHIPPING. DISCONTINUE USE IF ANY ADVERSE REACTION OR SYMPTOM OCCURS. CONTACT A DOCTOR IF REACTION OR SYMPTOM CONTINUES. FOR ADULTS ONLY. STORE OUT OF REACH OF CHILDREN.