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Koja je uloga limonena u modulaciji svojstava CBD-a protiv mučnine?

Koja je uloga limonena u modulaciji svojstava CBD-a protiv mučnine? Limonen modulira svojstva CBD-a protiv mučnine utječući na serotoninske receptore koji su uključeni u regulaciju mučnine i povraćanja. Pokazalo se da se limonen veže na 5-HT receptore i potiče antiemetičke učinke, nadopunjavajući djelovanje CBD-a u smanjenju mučnine kroz njegove interakcije s CB1 i CB2 receptorima. Zajedno, limonen i CBD nude sinergistički pristup upravljanju mučninom i povraćanjem, osobito kod kemoterapije ili druge mučnine izazvane liječenjem. Limonen također može povećati bioraspoloživost CBD-a, osiguravajući snažniji i dugotrajniji učinak protiv mučnine. Ova kombinacija može poboljšati terapijske rezultate za pojedince koji pate od kronične mučnine ili gastrointestinalnih poremećaja.

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