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Che ruolo gioca la dimensione molecolare dei cannabinoidi come CBN e CBG nella loro capacità di penetrare la barriera lipidica della pelle?

Che ruolo gioca la dimensione molecolare dei cannabinoidi come CBN e CBG nella loro capacità di penetrare la barriera lipidica della pelle? La dimensione molecolare dei cannabinoidi influenza la facilità con cui riescono a penetrare la barriera lipidica della pelle, poiché le molecole più piccole generalmente sono più efficienti nel passaggio. Il CBG e il CBN, come gli altri cannabinoidi, devono essere sufficientemente piccoli da potersi muovere attraverso lo strato corneo e raggiungere gli strati più profondi della pelle. Tuttavia, le molecole molto piccole potrebbero passare troppo velocemente, portando potenzialmente a velocità di rilascio non uniformi. Bilanciare le dimensioni molecolari con l’uso di potenziatori di penetrazione o sistemi a rilascio controllato può ottimizzare il rilascio dei cannabinoidi.

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