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In che modo i cannabinoidi come CBD e CBG influenzano il flusso sanguigno locale nel sito di applicazione del cerotto?

In che modo i cannabinoidi come CBD e CBG influenzano il flusso sanguigno locale nel sito di applicazione del cerotto? CBD e CBG possono influenzare il flusso sanguigno locale interagendo con i recettori dei cannabinoidi nella pelle, portando a vasodilatazione o vasocostrizione a seconda della dose e della risposta individuale. Gli studi suggeriscono che il CBD può favorire il flusso sanguigno attraverso i suoi effetti antinfiammatori, mentre è stato dimostrato che il CBG ha proprietà vasodilatatrici che migliorano la circolazione. L’aumento del flusso sanguigno locale può migliorare l’assorbimento dei cannabinoidi dal cerotto, potenziandone gli effetti terapeutici. Tuttavia, un’eccessiva vasodilatazione potrebbe anche portare ad una clearance più rapida, riducendo potenzialmente la durata dell’effetto.

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