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How can cannabinoid patches be adapted for patients with conditions that compromise their skin’s barrier function, like diabetes?

How can cannabinoid patches be adapted for patients with conditions that compromise their skin’s barrier function, like diabetes? Hypoallergenic adhesives and non-irritating carriers reduce the risk of skin damage in sensitive patients. Patches with occlusive backing can help retain moisture, supporting compromised barrier function. Slow-release formulations prevent sudden fluctuations in cannabinoid levels, which may be critical for individuals with metabolic disorders. Medical-grade materials and enhanced bioavailability strategies improve therapeutic safety and efficacy for these populations (Giacoppo et al., 2014).

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