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How does skin elasticity influence the absorption rate of cannabinoids in patches, especially in older populations?

How does skin elasticity influence the absorption rate of cannabinoids in patches, especially in older populations? Reduced skin elasticity in aging populations can affect patch adhesion and drug diffusion. Thinner, less hydrated skin may alter absorption rates, potentially leading to higher bioavailability. Formulating patches with flexible adhesives ensures consistent drug delivery across different skin conditions. Hydrating excipients improve skin integrity and optimize absorption in older adults (Baswan et al., 2020).

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