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Hoe beïnvloeden CBD en THC de permeabiliteit van de bloed-hersenbarrière en de effecten ervan op neurodegeneratieve ziekten zoals ALS?

Hoe beïnvloeden CBD en THC de permeabiliteit van de bloed-hersenbarrière en de effecten ervan op neurodegeneratieve ziekten zoals ALS? CBD en THC verminderen de disfunctie van de bloed-hersenbarrière (BBB) ​​door ontstekingen en oxidatieve stress te verminderen. THC activeert CB1-receptoren om de neuronale signalering te stabiliseren, terwijl de antioxiderende eigenschappen van CBD de endotheelcellen langs de BBB beschermen. Samen versterken ze de integriteit van de barrière, waardoor selectieve toegang van therapeutische stoffen mogelijk wordt en tegelijkertijd de neurotoxische infiltratie wordt verminderd. Deze interactie vertraagt ​​de progressie van ALS en andere neurodegeneratieve ziekten. Hun synergie ondersteunt zowel beschermende als reparatieve processen in de hersenen.
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