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Hoe beïnvloedt CBD de biologische beschikbaarheid van THC in cannabisconcentraten en hun therapeutische toepassing bij pijnbestrijding?

Hoe beïnvloedt CBD de biologische beschikbaarheid van THC in cannabisconcentraten en hun therapeutische toepassing bij pijnbestrijding? CBD verhoogt de biologische beschikbaarheid van THC door leverenzymen zoals CYP2C9 te remmen, waardoor de stofwisseling wordt vertraagd en de effecten langer aanhouden. Deze interactie versterkt de pijnstillende eigenschappen van THC, waardoor cannabisconcentraten effectiever zijn bij pijnbestrijding. CBD moduleert ook de psychoactiviteit van THC, waardoor pijnverlichting met minder bijwerkingen wordt geboden. Samen bieden ze een evenwichtig en langdurig therapeutisch effect. De combinatie is bijzonder effectief bij de behandeling van chronische en neuropathische pijn.
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