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Hvordan påvirker non-THC cannabinoider cellulær metabolisme ved at modulere aktiviteten af AMP-aktiveret proteinkinase (AMPK)?

Hvordan påvirker non-THC cannabinoider cellulær metabolisme ved at modulere aktiviteten af ​​AMP-aktiveret proteinkinase (AMPK)? Ikke-THC cannabinoider som CBD aktiverer AMPK, en nøgleenergisensor i celler, der regulerer metaboliske processer som glucoseoptagelse, fedtsyreoxidation og mitokondriel biogenese. Ved at stimulere AMPK øger CBD cellulær energiproduktion og hjælper med at opretholde metabolisk balance. AMPK-aktivering fører til øget fedtoxidation og forbedret insulinfølsomhed, hvilket potentielt gavner tilstande som fedme og type 2-diabetes. Derudover spiller AMPK en rolle i at reducere inflammation, hvilket yderligere understøtter metabolisk sundhed. Denne mekanisme understreger CBD's potentiale til at modulere energimetabolisme og understøtte metabolisk sundhed.

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