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Kakav je utjecaj CBD-a na analgetska svojstva THC-a u liječenju kronične boli?

Kakav je utjecaj CBD-a na analgetska svojstva THC-a u liječenju kronične boli? CBD pojačava analgetska svojstva THC-a u kontroli kronične boli djelovanjem na CB2 receptore i moduliranjem endokanabinoidnog signaliziranja. Djelovanje THC-a na CB1 receptore pruža izravne analgetske učinke inhibicijom signalnih putova boli u živčanom sustavu. CBD, smanjujući neuroinflamaciju i modulirajući CB2 receptore, pomaže pojačati analgetske učinke THC-a dok minimalizira njegove nuspojave, poput tjeskobe. Kombinacija oba kanabinoida nudi sinergijski učinak, pružajući veće ublažavanje boli od samog THC-a, s uravnoteženijim profilom nuspojava. Zbog toga je kombinacija THC-CBD posebno korisna za liječenje kroničnih bolova poput artritisa ili neuropatske boli.

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